Simply conducting the experiment myself, this seems to work perfectly fine. But your results may vary, so save a back-up of your mirc.ini file.
; To clear the CTRL+F find history in mdi windows.
//remini $mircini find2
; To clear the CTRL+F find history in script editor.
//remini $mircini find
; Optional. Just to be sure. Also type:
/saveini