From: versions.txt

25/11/95 - mIRC v3.8

Changes:
..
23.Added "me" prefix to remote definitions, eg.:
me:1:ON JOIN:/msg etc...
This limits a command definition to reacting only to
events caused by your client. This is useful in case you
use Bots which have the same address as you.

-

07/09/96 - mIRC v4.6

Changes:
..
50.Fixed "me:" prefix for remote definitions.