I had this problem occure all the time before multi-server support was implimented. I ran multiple instances of mIRC from the same directory and same INI file. Sometimes loading them too fast caused the mIRC.ini to lose information, so I created a 10 second timer between loading each instance. Sometimes if windows crashed quite violently, I would lose many .mrc files from the harddisk. It's possible that only files that mIRC has recently written to are effected (this includes .enable/.disabling #groups, etc).
Try performing a /saveini after you make any changes. There is also a program called Sync from
www.sysinternals.com that flushes all open files to the harddrive, physically. If this problem plagues you a lot, using both of these on an hourly timer might save you lots of grief.
- Raccoon
