It seems either the companies have underestimated the changes in Vista and/or began too late with coding new drivers and patches.
NVidia & Creative still don't have final versions of their drivers. Adobe has not and will not release patches for their current versions, instead they will force customers to buy new versions.
So it seems the Vista acceptance is not nearly as high when XP got out. I personally am content with XP and I think alot of people are content with it aswell and stay on XP as long as they can. As for mIRC, it would be indeed reasonable to offer Vista support, after 2-3 months.