See /help /font - You can change fonts for all an active type of window (i.e. all channels windows, all query windows etc) but, as yet, there is no option to change them all at the same time.
alias chfont scon -a chfont1 $1-
alias -l chfont1 {
if ($1 isnum) var %size = $1, %font = $$2-
else var %size = 14, %font = $$1-
var %i = $chan(0)
while (%i > 0) {
font -d $chan(%i) %size %font
dec %i
}
}