This is uTorrent's WebUI. It's very simple to set up. You just have to choose a port, a username, and a password. Then go to your browser, type http://IP:Port/gui and it prompts you to enter your username/password.
I think mIRC should have a similar feature. And I think it should be made user friendly.
This is a mockup I've made of what it could look like. Of course, it could also reflect your current mIRC theme/settings, but the default theme would already be a good start.
What do you guys think?