You can't in the matchtext itself but you can with an if statement. Example:
Code:
on *:TEXT:*Chandler*was*seen*:#: {
  ; used regex because there is no ISWMCS :(
  if ($regex($1-,Chandler.*was.*seen)) { msg #mychan $strip($1-) }
}


Perhaps a good feature suggestion would be a prefix for events that makes the matchtext case sensitive. ISWMCS has already been suggested.

pssst: close your code tag...