Code:
on *:TEXT:*:#: {
  var %x = /^(hello|hey|hi)\s $+ $me $+ /Si
  if ($regex($1-,%x)) {
    if $right($me,4) != -afk {
      describe # Hello $nick $+ , hows it going ? :)
    }
    else {
      describe # Sorry $nick $+ , but I'm not able to have a conversation with you at this time :)
  }
}

This works, just wondered if there was a better way to do it, such as having it all in the ON TEXT event, or if it makes any difference.