Yep, pretty easy to code smile This adds a toolbar button to remove hilights.
Code:
on *:start:toolbar -az1n20 UnMark "Unhilight all" mirc.exe /unmarkall
alias unmarkall scon -a _unmarkall
alias -l _unmarkall var %i = 1 | while $window(*,%i) { window -g0 $qt($v1) | inc %i }
For a different icon/picfile, change the blue text below (see /help /toolbar for info)
toolbar -az1n20 UnMark "Unhilight all" mirc.exe /unmarkall