never had problems with mIRC and games running at the same time, cpu usage is nicely low, and ram usage about normal (like 5 mb normal and 10mb if the channel buffers are filled up), you might try to unload some remote scripts with lots of timers in it, or disable logging

i have no problems with running UT(1), mirc and a winamp mp3 stream at the same time on a p600 512mb ram with a gf2mx400

if i put winamp off i c alil change in fps goin higher, but with mirc on or off UT(1) runs exactly the same i cant c any diffrence