All in all, don't expect mIRC to be 64-bit anytime soon. I hope this helps!
This. mIRC does not deal with nearly enough data for 64-bit to be worthwhile.
Due to Windows's architecture with WOW64, it is definitely true that mIRC is going to be slower as a 32-bit application than a 64-bit application. The reason is that mIRC makes a lot of system calls. However, mIRC is not a performance-intensive program, so despite this, any benefit from going 64-bit would be microscopic.
Contrast this with when mIRC went from 16-bit to 32-bit. (Yes, mIRC has been around that long. I first used mIRC on Windows 3.1.) Win32 had massive architectural improvements versus Win16, including the redesign of Winsock. The same is not true for 64-bit; in fact, Microsoft still calls the 64-bit Windows API "Win32".
Melissa