Actually, what FroggieDaFrog is implying does meet your goal, though I would argue is *less* useful to a user.

What he is implying is that you would hide the mouse cursor and then you can draw any custom cursor yourself using /drawpic

This is of course not ideal, since you would have to redraw the window every frame, which we all know mIRC is bad at handling.

The better generalized approach would be to allow mIRC to select *any* cursor icon from a dll/exe/ico the same way you can pick window icons, and have one of those indexes reserved for "no" cursor, which meets everyone's needs.