it seems you have 4 scripts loaded, one of which being popups.ini(?). Assuming this was a clean install of mIRC, there should be only 1 script loaded, and it should be empty.
Run a fresh copy of mIRC by copying mirc.exe into a new folder, creating an empty mirc.ini in the same folder and run the exe.
Basically the following:
//var %t = $mircdir..\testmirc | mkdir %t | .copy $mircexe %t | write -c %t $+ \mirc.ini | run %t $+ \mirc.exe
