No, not "negative". Poppy is right as well, many ppl have also reported getting that msg if they change nicks too often/fast. Altho there are diff raws for nick change too fast and target change too fast, i imagine it depends on the ircd. You can also get that msg if you try to join too many channels in too short a time.
For example, i believe Undernet prevents you from changing 20 targets per 2 minutes. A target is a 'Nick' or 'channel'. If you message more than 20 people or join more than 20 channels in two minutes then you'll start getting 'Target change too fast' and will have to wait before you can start talking. Helps cut down on spam.


ParaBrat @#mIRCAide DALnet