I confirm the same problem here.
It seems mIRC will transform most of my Latin characters if I use a Japanese locale, but only on keyboard input, copy/paste works fine.

That means à becomes a, é/è becomes e, and all of that regardless of messages option in mIRC, or of the input method, which, by the way, work perfectly fine in exlorer/ie/firefox/notepad/emeditor and most applications I have been using(ie, typing the key for é prints e, but copy/pasting é in the editbox works perfectly fine).

I think I reported this in the past, but without success.(that is no answers)