Quote:
can i set for some_file this: $mircdirsystem\something.exe
or i need to specify full path (eg c:\mirc\system\something.exe)

They are both the full path, so either will do

Quote:
also to ask, how to execute this too:
set __COMPAT_LAYER=DisableThemes

without runing 2 cmd's or its a must do (to run2 cmds) ?

Syntax is in my first post...
SET __COMPAT_LAYER=LayerName1 [layerName2] [layerName3]...

Code:
//run -n cmd.exe /c set __COMPAT_LAYER=Win2000 DisableThemes&& $qt(some_file)

Or, hiding the cmd window
Code:
//run -[color:green]h[/color] cmd.exe /c set __COMPAT_LAYER=Win2000 DisableThemes&& $qt(some_file)