yep.. look into the mIRC-Help under /speak ..
but i try this ms-agent-thing in the meantime and it works pretty fine. i only got some language-problems, because i (and the people in the chans i'm on) speak german and for this reason i have the german language engine installed, but it has little problems to pronounce english words the right way... =) .. maybe a multilanguage support for mIRC would come in handy..