You can store the words in %words like
%words www|http|com|net
then use a regular expression in the <matchtext> field (adding the $ prefix too):
on $^*:text:$($+(/,%words,/iS)):#: halt
Or you can put the words in a hash table (an item being a word surrounded by *'s, eg /hadd words *www*) and then check $hfind(words,$strip($1-),1,W) in the on TEXT event.