I don't think there's anything you can do manually that you can't do with a properly written script
I can personally guarentee that is not the case. I have a script that basically hides information in the message, that has to be picked up by the script as you can't visually see numbers after a color code, especially if I do a color code, number, then color code, when trying to hide that kind of information. Same with double bold codes with nothing between them, remotes can spot them, but if that's typed into the chat window, you aren't going to know it's there, and as a result, not be able to respond accordingly. But that's probably something that won't come up often. Most scripts will be able to be done manually.