I run 32-bit mIRC on 32-bit XP, but: my install is completely devoid of WoW16, NTVDM, and all their libraries and haven't had any problems, at least I have not run into something that uses a 16-bit api causing it not to function. Otherwise I don't recall wowexec/ntvdm running once during use (i always keep mirc open).
Last edited by bwuser; 03/02/07 11:33 AM.