XP users seem to be having a time of it with 10053 error, especially during dcc. YOu can read thru this thread
altho there are many many more, that one pretty much covers it.
Have you set your xp firewall up to allow dcc sends thru it? ditto your network and possibly your dsl settings. See this thread
Try disabling the xp firewall, and connecting to a server on any port other than 6667 and see if that helps.